Topic: Health and Safety

Xylazine Basics: Overdose Prevention, Harm Reduction, and Wound Care

This document provides information on xylazine, a non-opioid veterinary tranquilizer used as an additive in illicit drug supplies, notably in combination with heroin and fentanyl. It discusses the effects of xylazine use, including sedation and potential risks such as hypotension and bradycardia. The document also emphasizes harm reduction interventions for individuals who may encounter xylazine in the drug supply, including the use of naloxone for responding to overdoses and the importance of wound identification and treatment.

Native Harm Reduction Toolkit

This toolkit is a culturally responsive resource designed to help Native communities implement harm reduction strategies, decolonize public health approaches, reduce stigma, and engage Tribal leaders in supporting life-saving interventions.

Never Use Alone

Toll-free national overdose prevention, detection, life-saving crisis response and medical intervention services for people who use drugs while alone. Never Use Alone’s peer operators are available 24-hours a day, 7 days a week, 365 days a year.